I am fascinated about how cleverly our cells function. Since my early science steps I have been working with small molecule inhibitors and activators that can alter a cellular process (in my case autophagy) and potentially be used as disease treatments. This is how i understood that basic knowledge on the function of cellular pathways is really vital for the development and discovery of drugs that will be used to cure disease.
Understanding the molecular mechanisms of autophagy using ULK1 inhibitors.
MRC Protein Phosphorylation and Ubiquitylation Unit