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[New] Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition.

Research paper by Stéphanie S Arnould, Geneviève G Rodier, Gisèle G Matar, Charles C Vincent, Nelly N Pirot, Yoann Y Delorme, Charlène C Berthet, Yoan Y Buscail, Jean Yohan JY Noël, Simon S Lachambre, Marta M Jarlier, Florence F Bernex, Hélène H Delpech, Pierre Olivier PO Vidalain, Yves L YL Janin, et al.

Published on 22 Jul '17 in Oncotarget

3075 results for

Mitochondrial DNA depletion

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[New] Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition.

[New] Kanyawara Virus: A Novel Rhabdovirus Infecting Newly Discovered Nycteribiid Bat Flies Infesting Previously Unknown Pteropodid Bats in Uganda.

[New] MPV17 hepatocerebral mitochondrial DNA depletion syndrome presenting as acute flaccid paralysis - A case report.

[New] Adverse hematological effects of hexavalent chromium: an overview.

[New] Inhibition of mitochondrial translation effectively sensitizes renal cell carcinoma to chemotherapy.

[New] Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets.

[New] Mitochondrial DNA depletion induces innate immune dysfunction rescued by interferon-γ.

[New] Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes.

[New] Intracellular zinc flux causes reactive oxygen species mediated mitochondrial dysfunction leading to cell death in Leishmania donovani.

[New] Deubiquitinase Usp18 prevents cellular apoptosis from oxidative stress in liver cells.

[New] Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae.

[New] Genetic Counselling for Maternally Inherited Mitochondrial Disorders.

[New] Non-electron transfer chain mitochondrial defects differently regulate HIF-1α degradation and transcription.

[New] Nitric oxide is critical for avoiding hepatic lipid overloading via IL6 induction during liver regeneration after partial hepatectomy in mice.

[New] Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation.

[New] Deoxyguanosine kinase deficiency: a report of four patients.

[New] Novel RRM2B Mutation and Severe Mitochondrial DNA Depletion: Report of 2 Cases and Review of the Literature.

[New] Erythropoietin Activates SIRT1 to Protect Human Cardiomyocytes against Doxorubicin-Induced Mitochondrial Dysfunction and Toxicity.

[New] A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma.

[New] A novel mitochondrial ATP6 frameshift mutation causing isolated complex V deficiency, ataxia and encephalomyopathy.

[New] Neuroprotective effects of phloretin and its glycosylated derivative on rotenone-induced toxicity in human SH-SY5Y neuronal-like cells.

[New] Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1.

[New] Curcumin suppresses gastric tumor cell growth via ROS-mediated DNA polymerase γ depletion disrupting cellular bioenergetics.

[New] VDAC1 is a molecular target in glioblastoma, with its depletion leading to reprogrammed metabolism and reversed oncogenic properties.