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CURATOR

PhD Student, University of Stirling

PINBOARD SUMMARY

Identification of different phosphorylated protein in steady state and viral and bacterial PAMP stim

Aquaculture is one of the rising industry in the world. But, different diseases especially, bacterial and viral diseases are among the most important causes for losses to aquaculture industry, affecting the economic development of the sector in many countries. In my PhD programme, I am working on assessing virulence of fish and shellfish pathogens in host cells in vitro. I am trying to figure out the related genes expressed upon infection by different pathogens especially fish viruses like IPNV, ISAV, SAV etc. and fish and human pathogenic bacteria and how fish cells can be stimulated and activated against these pathogens using different stimulants. Protein phosphorylation is one of the post translation modifications of proteins which is involved in many regulatory mechanisms in eukaryotic cells. Phosphorylation of proteins plays key roles in innate immune response by activating different key players in signaling pathways which can answer many known unknown questions. Present study was thus conducted to identify the phosphorylated protein in steady state and viral and bacterial PAMP stimulated trout gill epithelial cells RTgill-W1.