Multiple sclerosis (MS) is the most common neurodegenerative disease. In MS patients immune system destroys myelin sheath around axons, leading to neural degeneration which is followed by various neurological dysfunctions. Fortunately, during remyelination process, spontaneous regenerative response to demyelination, new myelin sheaths are produced by oligodendrocytes. Neural stem cells (NSCs) have been demonstrated a great potential to produce new oligodendrocytes during remyelination. We investigate the role of NSCs in remyeliantion and molecular mechanisms regulating the behavior of these cells.
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