A pinboard by
Sashaina Fanibunda

Postdoctoral research associate, Tata Institute of Fundamental Research in collaboration with Kasturba Health Society, Medical Res Centre


Psychiatric disorders such as anxiety and depression are major sources of health burden across the globe. Mitochondrial metabolism plays a central role in the regulation of brain function and mitochondrial dysfunction has been implicated in psychiatric disorders. The molecular and cellular mechanisms that underlie such effects of altered mitochondrial activity/function in the development of alterations in mood-related behavior changes as well as stress associated changes in neuronal cytoarchitecture still remain unknown. Our current work focuses on investigating the role of neurotransmitters serotonin, norepinephrine and dopamine, as well as growth factors that impact mood, in the modulation of mitochondrial function within neurons.