Research Scholar, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus
Exploring wildly growing plants with medicinal properties for the development of "Herbal Medicine"
Herbal medicine is an important part of both traditional and modern system of medicines. It has been reported that over 50% of all modern clinical drugs are of natural origin and natural products play an important role in drug development programs in pharmaceutical industry. The development of novel drugs through the extraction of biologically active compounds from plants is the need of today’s research program, because emergence of Multi-drug resistance problem is a world wide problem in clinical medicine which is affecting our global health system.
Keeping in view of this, our study has been designed to isolate active compound from different wildly growing plants for the development of herbal medicine that would target resistant pathogens. We have identified active compound from Datura inoxia. The compound was found active against all the tested gram-positive and gram-negative strains. We have also identified its mechanisms of action, which confirms its bactericidal action and potential to be used as an alternative medicine. To further confirm the therapeutic applicability of compound, its in-vitro cytotoxicity assay was performed against mammalian cell line, which showed its non-toxic effect when incubated for different time intervals. To further strengthen the potential of our compound as herbal medicine, study on animal models are required.
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