Lecturer I, Head of Biochemistry Department, Bingham university, Nigeria
Prevention of colon cancer using natural products from edible plants
As an alternative approach, there is a need to consider that cancer is ultimately the end stage of a chronic disease. As such, we need to attempt to focus more effort on the control of carcinogenesis, rather than attempting to cure end-stage disease. Diets rich in fresh fruit and vegetables along with the absence of highly refined sugars have demonstrated a decrease in the risk for colon cancer. Current research on free radicals has also confirmed that food rich in antioxidants play essential role in the prevention of disease caused by oxidative stress (Iliemene and Atawodi, 2014; Vinita et al., 2013; Irondi et al., 2015). Therefore, plant-derived antioxidants are now receiving special attention. Our recent findings have shown that methanolic extract of the seeds of Dioclea reflexa and Brachystegia eurycoma possess appreciable antioxidant capacity (Iliemene and Atawodi, 2014; Irondi et al., 2015). Another recent study of ours provided bases to the folkloric use of the seeds of Dioclea reflexa and Brachystegia eurycoma as a remedy for preventing cancer especially colorectal cancer (Atawodi and Iliemene, 2017). Therefore, my current interest will be aimed at extending the study for isolation and structure determination of the colon cancer principle or principles present in the seeds which can be made into food supplement for easy access to everyone in Africa and the world at large. To also assess the relationship between the antioxidant properties of these commonly consumed seeds and disease prevention.