Student, Port City International University
Digital solution for global climate change
Artificial clouds to reflect away sunlight, creating colossal blooms of oceanic algae and the global use of synthetic carbon-neutral transport fuels are just three of the climate transforming technologies in need of urgent investigation, according to leading scientists. The eminent group argue that, with governments failing to grasp the urgent need for measures to combat dangerous climate change, radical – and possibly dangerous – solutions must now be seriously considered.
The idea of engineering on a planetary scale in a bid to control climate has been around for more than 50 years but, to date, has remained on the fringes. The potential for dramatic and beneficial change has hitherto been outweighed by the risk of unexpected side-effects in the complex climate system, with global consequences. Now, in a special edition of the journal Philosophical Transactions of the Royal Society, climate scientists and engineers have brought together the latest research and issued a call for a far-reaching assessment of a raft of geo-engineering techniques.
Abstract: To date, to enhance the mechanical properties of three-dimensional scaffolds used for bone regeneration in tissue engineering, many researchers have tried in the viewpoint of structure and chemistry. Meanwhile, in the structural engineering field, the kagome structure has been known as an excellent relative strength. In this study, to enhance the mechanical properties of a synthetic polymer scaffold used for tissue engineering, we applied the three-dimensional kagome structure to a porous scaffold for bone regeneration. Prior to fabricating the biocompatible-polymer scaffold, the ideal kagome structure, which was manufactured by a 3D printer of the digital light processing (DLP) type, was compared with a grid structure, which was used as the control group, using a compressive experiment. A polycaprolactone (PCL) kagome-structure scaffold was successfully fabricated by additive manufacturing using a 3D printer with a precision extruding deposition (PED) head. To assess the physical characteristics of the fabricated PCL-kagome-structure scaffold, we analyzed its porosity, pore size, morphological structure, surface roughness, compressive stiffness, and bending mechanical properties. The results showed that, the mechanical properties of proposed kagome-structure scaffold were superior to those of a grid-structure scaffold. Moreover, Sarcoma osteogenic (Saos-2) cells were used to evaluate the characteristics of in-vitro cell proliferation. We carried out cell counting kit-8 (CCK-8) and DNA contents assay. Consequently, the cell proliferation of the kagome-structure scaffold was increased; this could be because the surface roughness of the kagome-structure scaffold enhances initial cell attachment.
Pub.: 02 Aug '17, Pinned: 03 Aug '17
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