A pinboard by
Yusuf Hassan

Lecturer I, Umaru Musa Yar'adua University, Katsina, Nigeria


This work reports a new and efficient catalytic method for the Asymmetric Baylis-Hillman reaction.

This area termed "Asymmetric Synthesis" is a sub-area in a broader branch of Chemistry called Organic Chemistry. It focuses on the discovery and development of new, safe, and efficient method for carrying out some necessary and important step(s) in the process of making pharmaceutics and other biologically important compounds.

In this research, we have successfully developed a method that rely on using a little amount of chemical substance called catalyst to carry out a transformation popularly called Baylis-Hillman reaction. This transformation is widely used in the formation of products that possess many active sites that could provide an opportunity to further be manipulated in the process of making compounds that are medicinally important.

One of the beauties of the method developed here is that it is greener in nature, it means that it promotes Green Chemistry for sustainable development. Because the method requires little amount of chemical, energy, and ambient temperature for the reaction to take place. It also yield products in quite excellent yield, which is another important pillar of Green Chemistry.