Promoter or enhancer activation by CRISPRa rescues obesity

Last updated 29th Jun 2017
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A pinboard by Navneet Matharu

Postdoctoral Scholar, University of California San Francisco

PINBOARD SUMMARY

Universal platform technology to develop therapeutics for dosage sensitive diseases

Haploinsufficiency, having only one functional copy of a gene, leads to a wide range of human disease and has been associated with over 300 genes. Large-scale exome sequencing studies estimated tha...