Mechanoregulation of EMT transcription factor Twist1

Last updated 15th Jun 2017
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CURATOR

A pinboard by Laurent FATTET

Postdoctoral fellow, UCSD - Moores Cancer Center

PINBOARD SUMMARY

Increased stiffness drives breast tumor invasion and metastasis via mechanoregulation of Twist1.

Mechanical forces were recently recognized as potent regulatory signals of cellular behavior in various biological contexts. Matrix stiffness is controlled by deposition and modification of the ext...