Investigating the functional and adaptive role of polyglutamine tracts in yeast

Last updated 29th Jun 2017
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A pinboard by David Cooper

PhD Student, University of Iowa

PINBOARD SUMMARY

I study how polyglutamine tracts in transcriptional regulators may modulate protein function.

Polyglutamine (poly-Q) tracts are protein features prone to vary in length (number of repeats of the amino acid glutamine) due to the instability of the underlying repetitive DNA sequences. In some...