Deciphering metamorphosis of genetics codes; RNA alternative splicing

Last updated 2nd Mar 2020
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A pinboard by Htoo Aung Wai

Postdoctoral Research Fellow, University of Southampton


Protein sequences do not always reflect genetics code of DNA because of alternative splicing. Therefore, understanding DNA gene sequence alone is not enough, how DNA sequence is spliced is equally important in genomics era.

Messenger RNAs (mRNA) are transcribed from genes before translating to proteins. Human genome encodes over 20,000 genes but the estimated number of proteins in human is over 40,000. The ability to ...