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RECKONER: read error corrector based on KMC.

ABSTRACT

Presence of sequencing errors in data produced by next-generation sequencers affects quality of downstream analyzes. Accuracy of them can be improved by performing error correction of sequencing reads. We introduce a new correction algorithm capable of processing eukaryotic close to 500 Mbp-genome-size, high error-rated data using less than 4 GB of RAM in about 35 min on 16-core computer.Program is freely available at http://sun.aei.polsl.pl/REFRESH/reckoner CONTACT: sebastian.deorowicz@polsl.plSupplementary information: Supplementary data are available at Bioinformatics online.