Indexed on: 27 Oct '15Published on: 27 Oct '15Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disease which often accompany with abnormal fat distribution. Visceral adiposity has association with abnormal lipid metabolic, pro-inflammatory activity, insulin resistance (IR) and hyperandrogenism. Increased visceral adiposity raises the risk of metabolic syndrome, type 2 diabetes and cardiovascular (CV) events, and aggravates ovulatory dysfunction and hyperandrogenism in PCOS women. Visceral adiposity index (VAI), a simple surrogate maker of visceral adipose dysfunction and visceral adiposity, is a predictor of IR, and link hyperinsulinemia, hyperandrogenism and anovulation. This review aims to discuss the visceral adiposity situation in PCOS women, and suggests that VAI may be a useful predictor of clinical severity and therapeutic outcome of PCOS.
Indexed on: 30 Aug '16
Published on: 30 Aug '16 in Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Indexed on: 12 Oct '18
Published on: 12 Oct '18 in Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology