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Utilizing the eikonal relationship in strategies for reentrant wave termination in excitable media.

Research paper by Marcel M Hörning, Akihiro A Isomura, Zhiheng Z Jia, Emilia E Entcheva, Kenichi K Yoshikawa

Indexed on: 28 Sep '10Published on: 28 Sep '10Published in: Physical review. E, Statistical, nonlinear, and soft matter physics



Abstract

Obstacle-anchored vortices can be terminated by the application of high-frequency wave trains in excitable media. We theoretically derived the dependency between the obstacle radius and the maximum unpinning period through reinterpretation of the well-known eikonal equation. Our theoretical result was confirmed by experiments with cardiomyocyte monolayers. This result may be useful for improving the stimulation protocol of implantable cardiac pacemakers.