Unusual photophysical switching in a Ru(II) diimine DNA probe caused by amide functionalisation.

Research paper by Karen A KA O'Donoghue, John M JM Kelly, Paul E PE Kruger

Indexed on: 10 Sep '04Published on: 10 Sep '04Published in: Dalton Transactions


Whereas the complex [Ru(phen)2Medpq]2+(phen=1,10-phenanthroline; Medpq=2-methyldipyrido[3,2-f:2',3'-h]-quinoxaline) is luminescent in both aqueous and nonaqueous solutions, [Ru(phen)2dpqa]2+(2-pentylamidodipyrido[3,2-f:2',3'-h]-quinoxaline) does not emit in water but does so strongly in organic solvents or when bound to DNA--suggesting its use as a photochemical and photophysical probe for nucleic acids.