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Tuft Cells: New Players in Colitis.

Research paper by Shaun P SP Steele, Stephanie J SJ Melchor, William A WA Petri

Indexed on: 09 Oct '16Published on: 09 Oct '16Published in: Trends in Molecular Medicine



Abstract

A recent surge of interest in tuft cells, which are chemosensory intestinal epithelial cells, has uncovered new functional roles for these cells in colorectal cancer, metabolic signaling, and type 2 immunity. Here, we explore emerging evidence suggesting that tuft cells are critical for protection during enteric infections and inflammatory responses.