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Tubal cytokine changes accompany the epithelial atypia of letrozole-stimulated ovaries

Research paper by Ahmed A.M. Abdel-Hamid, Yaser Mesbah, Mona F.M. Farouk

Indexed on: 14 Mar '16Published on: 01 Feb '16Published in: Acta Histochemica



Abstract

Letrozole (LTZ), one of ovulation induction medications, is increasingly prescribed in many gynecological conditions. Although its hazardous effect on the ovarian surface epithelium (OSE) as well as tubal epithelium cells (TEC) has been previously studied, the associated changes occurring in the inflammatory cytokines have not been elucidated. Therefore, the objective of our study is to investigate these changes that may accompany LTZ-induced tubo-ovarian epithelial abnormalities.

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