Thrombotic pulmonary arteriopathy in polycythemia vera.

Research paper by C C Scharenberg, R R Riera, C C Görg, E M EM Walthers, P J PJ Barth

Indexed on: 03 Oct '99Published on: 03 Oct '99Published in: Pathology - Research and Practice


Pulmonary infarction and hemorrhage are important differential diagnoses in pulmonary coin lesions, especially in patients with underlying hematologic malignancies. We report a 58-year-old female patient suffering from polycythemia vera presenting with multiple pulmonary coin lesions. Open lung biopsy and subsequent histologic investigations showed organized pulmonary infarction and primary pulmonary thrombotic arteriopathy. Although histologic features are non-contributory in distinguishing organized thrombosis from organized thromboembolism, the clinical setting and localization of the lesions suggest that in the present case the vascular lesions are due to organized thrombosis.