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The role of mucin-type O-glycans in eukaryotic development.

Research paper by Lawrence A LA Tabak

Indexed on: 11 Feb '10Published on: 11 Feb '10Published in: Seminars in Cell and Developmental Biology



Abstract

Newly emerging genetic studies have revealed that a subset of the family of glycosyltransferases responsible for the formation of mucin-type O glycans is essential for normal development. As additional genetic, biochemical and physical tools are developed to interrogate the complex structure and surface location of this under-studied class of carbohydrate, no doubt additional roles will be elucidated.