Indexed on: 25 Jan '17Published on: 25 Jan '17Published in: Journal of the American Chemical Society
Metal-organic frameworks (MOFs) have rapidly grown into a major area of chemical research over the last two decades. MOFs represent the development of covalent chemistry 'beyond the molecule' and into extended structures. MOFs also present an unprecedented scaffold for performing organic transformations in the solid state, allowing for designed preparation of new materials. Development of these heterogeneous transformations has given rise to the 'postsynthetic renaissance,' a suite of methods by which these materials can be transformed in a single- crystal-to-single-crystal (SCSC) manner. Postsynthetic modification (PSM), postsynthetic deprotection (PSD), postsyn- thetic exchange (PSE), postsynthetic insertion (PSI), and postsynthetic polymerization (PSP) have exploited the unique features of both the organic and inorganic components of MOFs to create crystalline, porous solids of unprecedented complexity and functionality.