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The effect of amygdaloid lesions on feeding, grooming and reproduction in rats

Research paper by Neena B. Schwartz, Arthur Kling

Indexed on: 01 Mar '64Published on: 01 Mar '64Published in: Acta neurovegetativa



Abstract

Lesions of the amygdaloid nuclei were made in male and female post weaning but prepuberal rats. The majority of the operated animals died within two weeks of extreme inanition following complete aphagia and adipsia. A group of these aphagic animals was maintained for five months by force feeding. In addition, a small number of operated animals showed no disturbances in feeding and grew quite normally without force feeding. All of the survivingaphagic animals also showed tooth spiralling and did not groom. Reproductive performance, up to the delivery of the young (as far as was tested adequately) was normal in the operated females whether aphagic or not. The aphagic males did not mate (in spite of ongoing spermatogenesis and normal testis and seminal vesicle weight) but this is most likely a secondary effect of inanition on mating behaviour, not a direct effect of the lesion. Operated non-aphagic males showed normal fertility. No behavioral hypersexuality was observed in any of the operated males, but a number of males showed spontaneous ejaculations in the presence or absence of females. One of the aphagic males was also an “ejaculator” as was also an obese rat with an isolated lesion of the ventromedial nuclei of the hypothalamus. Anterior pituitary function seemed normal in all of the operated rats whether aphagic or not.