The benzoyl peroxide-promoted functionalization of simple alkanes with 2-aryl phenyl isonitrile.

Research paper by Wanxing W Sha, Jin-Tao JT Yu, Yan Y Jiang, Haitao H Yang, Jiang J Cheng

Indexed on: 06 Jul '14Published on: 06 Jul '14Published in: Chemical Communications


The benzoyl peroxide (BPO)-promoted phenanthridinylation of simple alkanes with isonitrile is developed via C(sp(3))-H and C(sp(2))-H bond cleavage. This procedure is featured by dual C-C bond formation proceeding with the addition of an alkyl radical to isonitrile followed by radical aromatic cyclization.