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Teaching resources. Regulation of complexes by cytoskeletal elements: integrins serve as force transducers linking mechanical stimuli and biochemical signals.

Research paper by Dan P DP Felsenfeld

Indexed on: 08 Dec '05Published on: 08 Dec '05Published in: Science's STKE : signal transduction knowledge environment



Abstract

This Teaching Resource provides a summary and slides derived from a lecture on the integrin family members and the downstream signaling pathways they activate; it is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture focuses on the capacity of integrins to serve as mechanotransducers, with particular emphasis on signaling mechanisms downstream of integrins.