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T-wave alternans testing for ventricular arrhythmias.

Research paper by Sanjiv M SM Narayan

Indexed on: 09 Sep '08Published on: 09 Sep '08Published in: Progress in Cardiovascular Diseases



Abstract

T-wave alterans (TWA) measures alternate-beat fluctuations in the ECG T-wave, and has been used to predict the risk for life-threatening ventricular arrhythmias in various clinical populations. This work reviews the traditional literature linking repolarization alternans in cellular and tissue-level studies, with clinical studies that TWA can successfully add to existing clinical risk factors in predicting ventricular arrhythmias. We conclude by providing an evidence-based framework integrating TWA with other risk factors to stratify risk for sudden cardiac arrest.