Systemic cidofovir in papillomatosis.

Research paper by I I Van Valckenborgh, W W Wellens, K K De Boeck, R R Snoeck, E E De Clercq, L L Feenstra

Indexed on: 15 Feb '01Published on: 15 Feb '01Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America


An 8-year-old patient with severe recurrent respiratory papillomatosis and pulmonary spread was treated by systemic administration of cidofovir in association with laser treatment for tracheal lesions. Complete disappearance of the lesions in the pharynx and larynx and a significant yet incomplete regression in the bronchi and lung parenchyma were observed without deleterious side effects. This is the first case report of systemic use of cidofovir to treat recurrent respiratory papillomatosis.