Indexed on: 16 Dec '11Published on: 16 Dec '11Published in: Journal of Medical Virology
Aciclovir (ACV)-resistant Herpes simplex virus type-2 (HSV-2) infections are observed commonly in patients also infected with HIV-1. The use of foscarnet (FOS) in these patients may also lead to resistance. This situation can become a difficult therapeutic challenge. Four cases of patients infected with HIV and with mucocutaneous HSV-2 resistant to ACV and FOS are reported. These patients were treated successfully with topical 5% imiquimod. Imiquimod treatment also appeared to delay the time to recurrence of HSV lesions.
Indexed on: 26 Sep '13
Published on: 26 Sep '13 in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America