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Substance Use Patterns of HIV-Infected Russian Women with and Without Hepatitis C Virus Co-infection.

Research paper by Jennifer L JL Brown, Ralph J RJ DiClemente, Jessica M JM Sales, Eve S ES Rose, Polina P Safonova, Olga S OS Levina, Nikolay N Belyakov, Vadim V VV Rassokhin

Indexed on: 21 Mar '16Published on: 21 Mar '16Published in: AIDS and behavior



Abstract

Individuals with HIV and hepatitis C virus (HCV) co-infection may experience substance use related health complications. This study characterized substance use patterns between HIV/HCV co-infected and HIV mono-infected Russian women. HIV-infected women (N = 247; M age = 30.0) in St. Petersburg, Russia, completed a survey assessing substance use, problematic substance use, and the co-occurrence of substance use and sexual behaviors. Covariate adjusted logistic and linear regression analyses indicated that HIV/HCV co-infected participants (57.1 %) reported more lifetime drug use (e.g., heroin: AOR: 13.2, 95 % CI 4.9, 35.3, p < .001), problem drinking (β = 1.2, p = .05), substance use problems (β = 1.3, p = .009), and increased likelihood of past injection drug use (AOR: 26.4, 95 % CI 8.5, 81.9, p < .001) relative to HIV mono-infected individuals. HIV/HCV co-infection was prevalent and associated with increased substance use and problematic drug use. Findings highlight the need for ongoing substance use and HIV/HCV risk behavior assessment and treatment among HIV/HCV co-infected Russian women.