Study of immune response to tumors in the rat.

Research paper by A B AB Frey

Indexed on: 01 Jun '97Published on: 01 Jun '97Published in: Methods


Use of the rat as host for the study of cancer has become popular for several reasons. The larger body size compared to mice is especially convenient for lines of experiments involving surgical manipulation, transplantation, or biochemical purification of molecules of interest. Immune response to cancer is also studied in rat models, and this article focuses on the methodological aspects of in vivo and in vitro protocols related to rat tumor immunology.