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Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy.

Research paper by Dongsheng D Duan, Jill A JA Rafael-Fortney, Alison A Blain, David A DA Kass, Elizabeth M EM McNally, Joseph M JM Metzger, Christopher F CF Spurney, Kathi K Kinnett

Indexed on: 01 Jan '16Published on: 01 Jan '16Published in: Journal of cardiovascular translational research



Abstract

A recent working group meeting focused on contemporary cardiac issues in Duchenne muscular dystrophy (DMD) was hosted by the National Heart, Lung, and Blood Institute in collaboration with the Parent Project Muscular Dystrophy. An outcome of this meeting was to provide freely available detailed protocols for preclinical animal studies. The goal of these protocols is to improve the quality and reproducibility of cardiac preclinical studies aimed at developing new therapeutics for the prevention and treatment of DMD cardiomyopathy.