Simultaneous treatment of ischaemic bowel and ischaemic stroke with intravenous thrombolysis therapy.

Research paper by Lucia Y LY Chen, Charlotte C Ainscough, Mohamed M Sayed, Maneesh M Bhargava

Indexed on: 21 Dec '18Published on: 21 Dec '18Published in: BMJ case reports


Novel treatment of simultaneous mesenteric and cerebral ischaemia with systemic thrombolysis. A 75-year-old man presented to the acute stroke team with aphasia, right-sided weakness and distressed with a pain he was unable to localise. He was treated with intravenous thrombolysis with tissue plasminogen activator for a left middle cerebral artery stroke. Decompensation on the ward during thrombolysis with worsening abdominal distension and pain, hypotension and tachycardia prompted a CT angiogram scan, which displayed proximal inferior mesenteric artery occlusion. Thrombolysis treatment resulted in excellent improvement of both his dysphasia and weakness from the left cerebral ischaemic stroke and reperfusion of the ischaemic bowel, without surgical intervention. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.