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Sequencing of a single HLA-B genotype including two rare alleles allows the detection of a new allele, B*44:130.

Research paper by D D Planelles, A A Balas, J A JA Montoro, R R Roig, J L JL Vicario

Indexed on: 29 Jun '11Published on: 29 Jun '11Published in: Tissue antigens



Abstract

The novel HLA-B*44:130 allele was found in a Spanish donor. B*44:130 differs from B*44:40 by four nucleotide changes at codons 11, 12 and 24, producing three amino acid replacements, 11A>S, 12M>V and 24T>S.