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Roles of NLRP10 in innate and adaptive immunity.

Research paper by Anna A Damm, Katja K Lautz, Thomas A TA Kufer

Indexed on: 09 Apr '13Published on: 09 Apr '13Published in: Microbes and Infection



Abstract

Mammalian nucleotide-binding domain leucine-rich repeat containing proteins (NLRs) are important pattern-recognition receptors, still the function of many NLRs remains poorly defined. Here we review first insights into the molecular function of NLRP10 highlighting the role of this specific NLR in innate and adaptive immune responses.