Quantcast

Rhodium-catalyzed direct synthesis of unprotected NH-sulfoximines from sulfoxides.

Research paper by Jinmin J Miao, Nigel G J NG Richards, Haibo H Ge

Indexed on: 16 Jul '14Published on: 16 Jul '14Published in: Chemical Communications



Abstract

A novel rhodium-catalyzed imination of sulfoxides using O-(2,4-dinitrophenyl)hydroxylamine is developed under mild conditions with good functional group tolerance. This method provides an efficient access to free NH-sulfoximines, an important structural unit in a variety of biologically active compounds.