Researches on imidazoles

Research paper by P. M. Kochergin, S. G. Verenikina

Indexed on: 01 Sep '65Published on: 01 Sep '65Published in: Chemistry of Heterocyclic Compounds


A number of 1-alkyl (1, 2-dialkyl)-4-nitro-5-alkyl (aryl, dialkyl) aminoimidazoles are synthesized by reacting 1-alkyl (1, 2-dialkyl)-4-nitro-5-chloroimidazoles with aliphatic, aromatic, and heterocyclic amines. Hydrogenation of 1-ethyl-2-methyl-4-nitro-5-(N-morpholino) imidazole in acetic anhydride gives 1-ethyl-2-methyl -4-diacetylamino-5-(n-morpholino) imidazole, characterized as its picrate.