Reactive intermediate detection in real time via paper assisted thermal ionization mass spectrometry.

Research paper by Jiying J Pei, Yanbiao Y Kang, Guangming G Huang

Indexed on: 23 Sep '14Published on: 23 Sep '14Published in: Analyst


To capture reactive intermediates from bulk solution in real time, mass spectrometry with paper assisted thermal ionization has been developed. Two representative organic reactions, Eschweiler-Clarke methylation at high temperature and acid-catalyzed olefin dioxygenation at room temperature, were chosen as models to evaluate the present method.