Reactions of tert-Butyl Tetraethylphosphorodiamidite with Acetic and Trifluoroacetic Acids

Research paper by L. K. Sal'keeva, M. T. Nurmagambetova, O. Sh. Kurmanaliev, T. Kh. Gazizov

Indexed on: 01 Feb '03Published on: 01 Feb '03Published in: Russian Journal of General Chemistry


Reactions of tert-butyl tetraethylphosphorodiamidite with acetic and trifluoroacetic acids involve substitution of the amido group. This process was described by a scheme beginning with protonation of phosphorus and proved by modeling separate reaction stages. A probable scheme of the proposed reactions is described.