Indexed on: 01 Mar '81Published on: 01 Mar '81Published in: Journal of Radioanalytical and Nuclear Chemistry
A series of idine-125 labeled ω-iodofatty acids were synthesized via a recently developed hydroboration-iodination sequence. The sequence involves the hydroboration of appropriate alkenoic acids with dialkylboranes followed by the reaction of the resultant organoborane with iodine-125 monochloride. The ω-iodofatty acids contained 11, 16, 19 and 22 carbons respectively. Isolated radiochemical yields were in the 85–95% range.