Protein-losing hypertrophic gastropathy: another cause of gastric wall thickening in children.

Research paper by Víctor V Pineda, Goya G Enriquez, Francisco F Castelló, Celestino C Aso

Indexed on: 06 Jan '04Published on: 06 Jan '04Published in: Journal of Clinical Ultrasound


Protein-losing hypertrophic gastropathy (PLHG) is an uncommon, self-limited disease in young children that can produce generalized edema, hypoproteinemia, and nonspecific prodromic symptoms. Recently, Helicobacter pylori and cytomegalovirus infections have been reported to be associated with this condition. We present the case of an 18-month-old boy with PLHG and positive detection of H. pylori on fecal culture. Abdominal sonography demonstrated gastric wall thickening with preservation of the mucosal layers. Sonographic findings are useful for suggesting a diagnosis of PLHG and is also an effective, noninvasive technique for follow-up of children with this condition.