Quantcast

Programmed Death - Ligand 1 Expression Distinguishes Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma from Noninvasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features

Research paper by Guodong Fu, Olena Polyakova, Christina MacMillan, Ranju Ralhan, Paul G. Walfish

Indexed on: 01 Apr '17Published on: 24 Mar '17Published in: EBioMedicine



Abstract

The noninvasive Encapsulated follicular variant of papillary thyroid cancer (EFVPTC) has been reclassified as Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) without a significant risk for malignant behavior. However the evaluation remains a challenge for clinicians. We sought to determine whether programmed death-ligand 1 (PD-L1) expression may serve as a biomarker to predict invasiveness of EFVPTC and assist to distinguish these neoplasms from NIFTP.

Figure 10.1016/j.ebiom.2017.03.031.0.jpg
Figure 10.1016/j.ebiom.2017.03.031.1.jpg
Figure 10.1016/j.ebiom.2017.03.031.2.jpg