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Primary cutaneous mucormycosis in a lung transplant recipient: case report and concise review of the literature.

Research paper by A V AV Page, A J AJ Evans, L L Snell, W C WC Liles

Indexed on: 17 Jul '08Published on: 17 Jul '08Published in: Transplant Infectious Disease



Abstract

Mucormycosis (zygomycosis) is an invasive, opportunistic fungal infection caused by organisms of the class Zygomycetes. Immunocompromised individuals, including both solid organ and hematopoietic stem cell transplant recipients, are preferentially affected. Among solid organ transplant (SOT) recipients, the sinuses, with or without involvement of the orbits and cerebrum, are the most common sites of disease, although the pulmonary allograft appears to be targeted following lung transplantation. Here, we describe the unique case of a lung transplant recipient who developed multifocal cutaneous mucormycosis without involvement of the pulmonary allograft, and review the published literature regarding incidence, treatment, and prognosis of primary cutaneous mucormycosis following SOT.