Primary Adenocarcinoma of an Ileostomy in Crohn's Disease.

Research paper by Kevin K Liu, Meena A MA Prasad, Amy A Lo, Emanuelle E Bellaguarda, Scott S Strong, Stephen B SB Hanauer

Indexed on: 14 Sep '16Published on: 14 Sep '16Published in: ACG case reports journal


Although Crohn's disease has been associated with an increased risk of small bowel adenocarcinoma, primary adenocarcinoma arising from an ileostomy is a complication that has been rarely documented in Crohn's disease. Chronic small bowel inflammation may lead to development of malignancy through the dysplasia-carcinoma sequence. We report a case of a 61-year-old woman with Crohn's ileocolitis diagnosed with a primary adenocarcinoma at the ileostomy with metastases to the liver 47 years after proctocolectomy, and review the literature.