Prevalence of Dementia and Mild Cognitive Impairment in the Rural Island Town of Ama-cho, Japan.

Research paper by Kenji K Wada-Isoe, Yusuke Y Uemura, Satoko S Nakashita, Mika M Yamawaki, Kenichiro K Tanaka, Mikie M Yamamoto, Hiroshi H Shimokata, Kenji K Nakashima

Indexed on: 22 Jun '12Published on: 22 Jun '12Published in: Dementia and geriatric cognitive disorders extra


In order to determine the prevalence of dementia and mild cognitive impairment (MCI), we conducted a population-based study in Japan.Participants included 924 subjects aged 65 years or older who resided in the town of Ama-cho. In phase 1 of the study, the Mini-Mental State Examination and Clinical Dementia Rating were administered for screening purposes. In phase 2 of the study, the subjects who screened positive were further examined by neurologists. Dementia and MCI were diagnosed by means of DSM-IV and International Working Group on MCI criteria, respectively.By the prevalence date of June 1, 2010, 24 subjects had deceased or lived outside the town. In total, 723 of the remaining 900 subjects received a phase 1 test. In phase 2, 98 subjects were diagnosed with amnestic MCI, 113 subjects with non-amnestic MCI, and 82 subjects with dementia. Of the subjects who did not receive the phase 1 test, 66 subjects were diagnosed as having dementia according to data from their town medical card or the Long-term Care Insurance System. The crude prevalence of amnestic MCI, non-amnestic MCI, and dementia were 10.9, 12.6, and 16.4%, respectively.Consistent with the striking increase in the number of elderly individuals, we report higher prevalence of MCI and dementia in Japan than previously described.