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Positively selecting peptides: their job does not end in the thymus.

Research paper by Kai W KW Wucherpfennig, Etienne E Gagnon

Indexed on: 21 Oct '09Published on: 21 Oct '09Published in: Nature Immunology



Abstract

Peptides able to positively select major histocompatibility complex class II-restricted thymocytes have not yet been defined. Two new reports identify and ascribe important extrathymic functions to several positively selecting peptides for CD4+ T cells.