Plummer-Vinson Syndrome with Proximal Esophageal Web

Research paper by Kinesh Changela, Nami Safai Haeri, Mahesh Krishnaiah, Madhavi Reddy

Indexed on: 29 Apr '16Published on: 09 Dec '15Published in: Journal of Gastrointestinal Surgery


Plummer-Vinson Syndrome is a condition where iron deficiency is associated with difficulty swallowing due to the presence of an esophageal web. Deficiency of iron-dependent oxidative enzymes causes gradual degradation of the pharyngeal muscles which lead to mucosal atrophy and formation of webs. Although it is a very rare condition, an increased risk of esophageal squamous cell carcinoma makes its identification very important. Dilation of the esophageal web using a Savary dilator is a more effective and safer approach compared to conventional balloon dilation.