Pleomorphic corneal sarcoma resembling malignant peripheral nerve sheath tumor in a horse.

Research paper by E C EC Kappe, K K Köhler, I V IV Felbert, J P JP Teifke, J J Tóth, M M Reinacher

Indexed on: 30 Jan '09Published on: 30 Jan '09Published in: Veterinary pathology


A 14-year-old Haflinger gelding presented with a protruding mass involving the cornea of the right eye. The mass was resected and submitted for histopathologic and immunohistochemical examination. The preliminary diagnosis was corneal sarcoma, most likely fibrosarcoma. The immunohistochemical results confirmed the mesenchymal origin of the neoplastic cells, which were most consistent with a malignant peripheral nerve sheath tumor. Corneal mesenchymal neoplasms are extremely uncommon tumors in human beings and domestic animals. The cause for this tumor was not determined; infection with bovine papillomavirus was not detected.