Pd-Catalyzed 1,2-diarylation of vinylarenes at ambient temperature

Research paper by Zhijie Kuang, Kai Yang, Qiuling Song

Indexed on: 22 Mar '17Published on: 08 Mar '17Published in: Organic Chemistry Frontiers


An efficient Pd-catalyzed three components reaction involving the 1,2-diarylation of vinylarenes has been disclosed. This reaction introduces two different aryl groups across vinylarenes at ambient temperature giving rise to multi-aryl substituted ethanes which are biologically relevant compounds prevailing in organic chemistry, medicinal chemistry and materials science.

Graphical abstract 10.1039/C7QO00097A.gif