Optimizing the relaxivity of GdIII complexes appended to InP/ZnS quantum dots by linker tuning.

Research paper by Graeme J GJ Stasiuk, Sudarsan S Tamang, Daniel D Imbert, Christelle C Gateau, Peter P Reiss, Pascal P Fries, Marinella M Mazzanti

Indexed on: 15 May '13Published on: 15 May '13Published in: Dalton Transactions

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Abstract

Three bimodal MRI/optical nanosized contrast agents with high per-nanoparticle relaxivity (up to 2523 mM(-1) s(-1) at 35 MHz and 932 mM(-1) s(-1) at 200 MHz) have been prepared connecting up to 115 tris-aqua Gd(III) complexes to fluorescent non-toxic InP/ZnS quantum dots. The structure of the linker has an important effect on the relaxivity of the final multimeric contrast agent.

Optimizing the relaxivity of GdIII complexes appended to InP/ZnS quantum dots by linker tuning.

Abstract

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Optimizing the relaxivity of GdIII complexes appended to InP/ZnS quantum dots by linker tuning.

Abstract

More like this:

Calix[4]arenes as molecular platforms for magnetic resonance imaging (MRI) contrast agents.

Synthesis and relaxivity studies of a tetranuclear gadolinium(III) complex of DO3A as a contrast-enhancing agent for MRI.

Densely packed Gd(III)-chelates with fast water exchange on a calix[4]arene scaffold: a potential MRI contrast agent.

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