Operant performance in inbred mice

Research paper by Richard L. Sprott, James P. Symons

Indexed on: 07 Nov '13Published on: 07 Nov '13Published in: Bulletin of the Psychonomic Society


The procedures described in this report are standard operant procedures, which have been used successfully to condition mice to barpress for a food reward on a variety of schedules of reinforcement. The schedules of reinforcement include continuous reinforcement, nine fixed ratio values, and six fixed interval values. Mice of five genotypes have been exposed to some or all of these schedules. Performance was typical of that observed in other organisms, and satiation was not a problem in sessions lasting from 2 to 31/2 h. This experiment clearly demonstrated that barpress performance can be obtained with inbred mice as readily as with other organisms.